ChemicalBook > CAS DataBase List > 2',3'-DIDEOXY-3'-FLUOROURIDINE

2',3'-DIDEOXY-3'-FLUOROURIDINE

Product Name
2',3'-DIDEOXY-3'-FLUOROURIDINE
CAS No.
41107-56-6
Chemical Name
2',3'-DIDEOXY-3'-FLUOROURIDINE
Synonyms
Fddurd;2',3'-DIDEOXY-3'-FLUOROURIDINE;2',3'-DIDEOXY-3'-FLUOROURIDINE;3'-FLUORO-2',3'-DIDEOXYURIDINE;URIDINE, 2',3'-DIDEOXY-3'-FLUORO-;2’,3’-Dideoxy-3’-fluorouridine, FddU;2',3'-DIDEOXY-3'-FLUOROURIDINE USP/EP/BP;2’,3’-Dideoxy-3’-fluorouridine, FddU, anti-HIV;1-(2,3-DIDEOXY-3-FLUORO-BETA-D-RIBOFURANOSYL)URACIL;5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran
CBNumber
CB2779445
Molecular Formula
C9H11FN2O4
Formula Weight
230.19
MOL File
41107-56-6.mol
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2',3'-DIDEOXY-3'-FLUOROURIDINE Property

Melting point:
184-188 °C(lit.)
Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Water
form 
Solid
pka
9.39±0.10(Predicted)
color 
White to Off-White
optical activity
[α]20/D +10.5°, c = 0.5 in 1 M NaOH
BRN 
6064366
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Safety

Hazard Codes 
Xn
Risk Statements 
68
Safety Statements 
22-36/37
WGK Germany 
1
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H341Suspected of causing genetic defects

Precautionary statements

P281Use personal protective equipment as required.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
393711
Product name
2′,3′-Dideoxy-3′-fluorouridine
Purity
95%
Packaging
25mg
Price
$223
Updated
2022/05/15
Sigma-Aldrich
Product number
393711
Product name
2′,3′-Dideoxy-3′-fluorouridine
Purity
95%
Packaging
100mg
Price
$695
Updated
2022/05/15
TRC
Product number
D439960
Product name
2'',3''-Dideoxy-3''-fluorouridine
Packaging
250mg
Price
$745
Updated
2021/12/16
TRC
Product number
D439960
Product name
2'',3''-Dideoxy-3''-fluorouridine
Packaging
10mg
Price
$90
Updated
2021/12/16
TRC
Product number
D439960
Product name
2'',3''-Dideoxy-3''-fluorouridine
Packaging
25mg
Price
$130
Updated
2021/12/16
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2',3'-DIDEOXY-3'-FLUOROURIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

2'',3''-Dideoxy-3''-fluorouridine is a reactant used in the synthesis of 5''-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase.

Uses

2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:

  • 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.
  • 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.

General Description

2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.

2',3'-DIDEOXY-3'-FLUOROURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2',3'-DIDEOXY-3'-FLUOROURIDINE Suppliers

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41107-56-6, 2',3'-DIDEOXY-3'-FLUOROURIDINERelated Search:

3'-Deoxy-3'-fluorothymidine 2',3'-DIDEOXY-3'-FLUOROURIDINE 3'-Deoxy-3'-fluoro-5'-O-trityl-D-thymidine 5'-O-ACETYL-2'-3'-DIDEOXY-3'-FLUORO-URIDINE 5-CHLORO-2',3'-DIDEOXY-3'-FLUORO-URIDINE FOSALVUDINE TIDOXIL 2',3'-dideoxy-5-fluorouridine 3'-Azido-2',3'-dideoxy-5-fluorouridine 5-fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate 5'-O-Benzoyl-3'-fluoro-2',3'-dideoxyuridine AURORA KA-635 5'-O-Anisoyl-3'-fluoro-2',3'-dideoxyuridine 3'-Fluoro-5'-O-toluoyl-2',3'-dideoxyuridine 3'-FLUORO 3'-DEOXYTHYMIDINE, [METHYL-3H(N)]- AURORA KA-625 AURORA KA-603 5'-O-t-Butyldimethylsilyl-3'-fluoro-2',3'-dideoxyuridine AURORA KA-624

  • URIDINE, 2',3'-DIDEOXY-3'-FLUORO-
  • 3'-FLUORO-2',3'-DIDEOXYURIDINE
  • 2',3'-DIDEOXY-3'-FLUOROURIDINE
  • 5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran
  • Fddurd
  • 1-(2,3-DIDEOXY-3-FLUORO-BETA-D-RIBOFURANOSYL)URACIL
  • 2’,3’-Dideoxy-3’-fluorouridine, FddU
  • 2',3'-DIDEOXY-3'-FLUOROURIDINE USP/EP/BP
  • 1-((2R,4S,5R)-4-Fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 2’,3’-Dideoxy-3’-fluorouridine, FddU, anti-HIV
  • 2',3'-DIDEOXY-3'-FLUOROURIDINE
  • 41107-56-6
  • C9H11FN2O4
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrimidines
  • Nucleosides
  • Oligonucleotide Synthesis
  • Specialty Synthesis
  • Heterocyclic Compounds